| 货号:SPR-300B | 规格:100 µg | 目录价:¥4599 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Human Recombinant AHA1 Protein
别名:
Aha1 Protein, SHSA1 Protein, HSPC322 Protein, p38 Protein
产品描述:
Human Recombinant AHA1 Protein
反应种属:
Human
实验应用:
WB | SDS-PAGE | Functional Assay
纯化方式:
Multi-Step Purified
偶联:
No tag
产品浓度:
Lot/batch specific. See included datasheet.
表达系统:
E. coli
保存温度:
-20ºC
运输温度:
Blue Ice or 4ºC
预期分子量:
~38 kDa
存储溶液:
20mM HEPES buffer pH7.2, 80mM NaCl, 10% glycerol
产地:
加拿大
功能与背景:
Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).
纯度:
>90%
Accession #:
NP_036243.1
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