Human Recombinant HOP Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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Human Recombinant HOP Protein

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPR-302A

规格：50 µg

目录价：￥2305.8

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human Recombinant HOP Protein

别名:

HSP co chaperone Protein

产品描述:

Human Recombinant HOP Protein

反应种属:

Human

实验应用:

WB | SDS-PAGE | Functional Assay

纯化方式:

Affinity Purified

偶联:

His tag

产品浓度:

Lot/batch specific. See included datasheet.

表达系统:

E. coli

保存温度:

-20ºC

运输温度:

Blue Ice or 4ºC

预期分子量:

~63 kDa

存储溶液:

25mM HEPES pH 7.2, 50mM NaCl, 1mM DTT, 10% glycerol

产地:

加拿大

功能与背景:

Hop (HSP70/HSP90 Organizing Protein), or Stress-induced Phosphoprotein 1 (STI1) as it is also known, is a 60kDa protein that belongs to the large group of co-chaperones which regulate and assist the major chaperones. It is located in diverse cellular regions and can move between the cytoplasm and the nucleus. It functions to reversibly link together the protein chaperones HSP70 and HSP90. HOP contains three tetratricopeptide repeat (TPR) domains, TPR1, TPR2a and TPR2b. HSP70 binding has been localized to TRP1 and sp90 binding have been localized to TPR2a (1). It has also been found to modulate the chaperone activities of the linked proteins and possible interacts with other chaperones and proteins. It has also been found to participate in other complexes besides the HSP70/HSP90 one (2). HOP is closely related to human 63kDa protein that is sensitive to simian virus SV40 transformation, and is related to the yeast heat-shock- responsive STI1 gene product (3, 4).

纯度:

>90%

Accession #:

NP_006810.1

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