KDEL Antibody: ATTO 488-多抗-深圳欣博盛生物科技有限公司

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KDEL Antibody: ATTO 488

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SPC-109B-A488

规格：200 µg

目录价：￥5481

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

KDEL Antibody: ATTO 488

别名:

Lys Asp Glu Leu Antibody

产品描述:

Rabbit Anti-KDEL Polyclonal

反应种属:

Human | Mouse | Rat

宿主来源:

Rabbit

实验应用:

WB | ICC/IF | IHC

靶标/特异性:

Detects KDEL proteins, GRP94, Grp78, PDI and calreticulin. It may also see ERp57 and ERp29.

推荐稀释度:

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

KDEL containing peptide immunogen

克隆性:

Polyclonal

纯化方式:

Protein A Purified

偶联:

ATTO 488

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.2, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER.