| 货号:SPC-109B-A594 | 规格:200 µg | 目录价:¥5481 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
KDEL Antibody: ATTO 594
别名:
Lys Asp Glu Leu Antibody
产品描述:
Rabbit Anti-KDEL Polyclonal
反应种属:
Human | Mouse | Rat
宿主来源:
Rabbit
实验应用:
WB | ICC/IF | IHC
靶标/特异性:
Detects KDEL proteins, GRP94, Grp78, PDI and calreticulin. It may also see ERp57 and ERp29.
推荐稀释度:
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
免疫原:
KDEL containing peptide immunogen
克隆性:
Polyclonal
纯化方式:
Protein A Purified
偶联:
ATTO 594
产品浓度:
1 mg/ml
保存温度:
Conjugated antibodies should be stored according to the product label
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS pH7.2, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER.
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