| 货号:SYN-1002-M001 | 规格:1 mg | 目录价:¥1204 |
| 货号:SYN-1002-M005 | 规格:5 mg | 目录价:¥1820 |
| 货号:SYN-1002-M010 | 规格:10 mg | 目录价:¥3024 |
| 货号:SYN-1002-M050 | 规格:50 mg | 目录价:¥8316 |
| 货号:SYN-1002-M100 | 规格:100 mg | 目录价:¥询价 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Linifanib
别名:
ABT-869; AL39324; RG-3635
产品描述:
Linifanib (A 741439; A-741439; A741439; ABT-869; ABT869; RG3635) is an orally active multi-targeted receptor tyrosine kinase inhibitor for the treatment of various cancers. The compound is designed to inhibit vascular endothelial growth factor and platelet-derived growth factor receptors and is a multitargeted tyrosine kinase receptor inhibitor that suppresses FLT3 signaling. It is in phase III development for liver cancer and phase II development for non-small cell lung cancer, breast cancer, and colorectal cancer. Recent research also indicates that Linifanib inhibits proliferation and induces apoptosis in AML patient cells via reduction of AKT and GSK3beta phosphorylation and maybe influencial in AML therapy.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
375.4
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
796967-16-3
分子式:
C21H18FN5O
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