Osthole-其他小分子化合物-深圳欣博盛生物科技有限公司

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Osthole

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-O0097-M010	规格：10 mg	目录价：￥1106
货号：CDX-O0097-M050	规格：50 mg	目录价：￥2576

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Osthole

别名:

7-Methoxy-8-(3-methyl-2-butenyl)coumarin; 7-Methoxy-8-isopentenylcoumarin; NSC 31868

产品描述:

Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens. Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-alpha, NF-kappaB, TGF-beta, cyclooxygenases, leukotrienes, nitric oxide, ERK and JNK. Shows also anti-cancer, chemopherapeutic, analgesic, neuroprotective, antipruritic, anti-leishmania and anti-lipedemic activities. It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects. Selectively inhibits TRPV3 channels in skin. Induces apoptosis and cell cycle arrest in cancer cells. Suppression of fatty acid synthase expression in HER2-overexpressing breast cancer cells indicates osthole as a promising agent for chemotherapy.

宿主来源:

Synthetic

保存温度:

+20°C

运输温度:

Ambient

预期分子量:

244.29

产品形式:

solid

产地:

瑞士