官网链接
折扣/货期| 货号：AG-CN2-0078-G001 | 规格：1 g | 目录价：￥7080 |
| 货号：AG-CN2-0078-M025 | 规格：25 mg | 目录价：￥420 |
| 货号：AG-CN2-0078-M100 | 规格：100 mg | 目录价：￥1320 |
| 货号：AG-CN2-0078-M250 | 规格：250 mg | 目录价：￥2280 |
| 货号：AG-CN2-0078-M500 | 规格：500 mg | 目录价：￥4200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Puromycin . dihydrochloride
别名:
CL16,536; NSC 3055; Stylomycin
产品描述:
Aminonucleoside antibiotic. Protein synthesis inhibitor. Disrupts peptide transfer on ribosomes (acting as an acyl-tRNA analog) causing premature chain termination during translation. Translational inhibitor in prokaryotic and eukaryotic cells in both in vitro and in vivo systems. Inhibits the transport of proteins into the mitochondria in vitro. Reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase (metallopeptidase). Apoptosis inducer. Inhibits the growth of Gram-positive bacteria, various animal and insect cells. Fungi and Gram-negative bacteria are resistant due to the low permeability to the antibiotic. Antineoplastic agent. Used in cell biology as selective agent in cell culture systems. It allows selection for cells that contain the resistance gene puromycin N-acetyl-transferase (PAC). Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 µg/ml, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 µg/ml. Puromycin-resistant stable mammalian cell lines can be generated in less than one week.
宿主来源:
Isolated from Streptomyces alboniger.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
471.5 . 72.9
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
58-58-2
分子式:
C22H29N7O5 . 2HCl
溶解度:
Soluble in water.
促销活动
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