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折扣/货期| 货号：SIH-389-100MG | 规格：100 mg | 目录价：￥907.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Tamoxifen Citrate
别名:
(2)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine citrate
产品描述:
Autophagy inducer
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
563.65
产品形式:
White to off-white powder
产地:
加拿大
功能与背景:
Tamoxifen citrate is an endocrine therapy drug used to treat breast cancer. It acts to interrupt estrogen signaling by blocking the estrogen receptor (ER). In vivo, tamoxifen and tamoxafin metabolites bind to estrogen receptors, causing the transcription of estrogen-response genes to be inhibited. In vitro, Tamoxifen is known to inhibit protein kinase C through estrogen receptor-independent antineoplastic effects. This drug therefore has important applications in breast cancer research, particularly in ER+ breast cancers. Recent studies have shown tamoxifen-resistant cells use autophagy as a survival mechanism.
纯度:
≥99%
来源:
Synthetic
CAS号:
54965-24-1
分子式:
C26H29NO•C6H8O7
溶解度:
Soluble in methanol (50 mg/ml) or ethanol; very slightly soluble in water or acetone.
PubChem CID:
2733525
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