Xanthohumol-其他小分子化合物-深圳欣博盛生物科技有限公司

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Xanthohumol

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CDX-X0005-M025	规格：25 mg	目录价：￥4060
货号：CDX-X0005-M050	规格：50 mg	目录价：￥6440

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Xanthohumol

别名:

2',4,4'-Trihydroxy-6'-methoxy-3'-prenylchalcone

产品描述:

Xanthohumol is a cell-permeable natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via the nuclear factor erythroid-2-related factor 2 pathway. Xanthohumol can have anti-inflammatory, antioxidant, anticarcinogenic, antidiabetic and osteogenic effects. Xanthohumol binds to the N-terminal domain of p97 ATPase (VCP; valosin-containing protein), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of p97 ATPase thereby impairing autophagosome maturation and resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II)1. Xanthohumol inhibits diacylglycerol acetyltransferase (DGAT) and human P450 enzymes. It also inhibits the expression of HIF-1alpha and VEGF under hypoxic conditions.

宿主来源:

Plant

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

354.4

产品形式:

solid

产地:

瑞士