深圳欣博盛生物科技有限公司 a1

Sorafenib tosylate
货号:CDX-S0264-G005 规格:5 g 目录价:¥1050
货号:CDX-S0264-G025 规格:25 g 目录价:¥4200
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Sorafenib tosylate
别名:
Sorafenib p-toluenesulfonate; Nexavar; ,BAY 43-9006 mono-p-tosylate; BAY 54-9085
产品描述:
Sorafenib tysolate is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6n and 22nM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, Flt-3, c-Kit, FGFR-1 (Flt-2) and RET, involved in neovascularization and tumor progression. It is selective for these kinases over 12 other kinases, including ERK1, MEK1, EGFR, and HER2 (IC50s = >10µM for all). Sorafenib tosylate exerts broad-spectrum anticancer activity and disrupts signaling pathways that are vital for tumor growth and angiogenesis.
宿主来源:
Synthetic
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
637.03
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
475207-59-1
分子式:
C21H16ClF3N4O3 . C7H8SO3
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